After that, Quinton de Kock (right) and Rilee Rossouw took control as the two South Africans began piling on the runs, hitting boundaries regularly in a 90-run stand for the 2nd wicket.
De Kock looked in fine touch and struck a second consecutive fifty. He made 68 off 43 with the help of six fours and four sixes before departing.
Rossouw left behind his two ducks in the first two matches as he struck a maiden T20I century to remain inbeaten on 100 off 48. South Africa finished with 227/3 in 20 Overs.
Kagiso Rabada then landed a major blow when he bowled India captain Rohit Sharma with the second delivery of the chase.
India lost two wickets early before a brief recovery courtesy Dinesh Karthik (in picture) and Rishabh Pant with the pair adding 41 runs in quick time.
However, none of the India batters converted their starts with Karthik falling on 46 while Pant hitting 27. It was an off-day for Suryakumar Yadav who managed 8.