Why the situation became uncontrollable in the second wave of Corona in India, know the reason

Coronavirus India | The reason for the sudden lifting of the second wave of corona in April is the sudden end of one mutation in the delta variant and the birth of another. Researchers from the Council of Scientific and Industrial Research (CSIR) say that this mutation suddenly caused the delta variant to become uncontrollable and it even outnumbered the then slowly spreading UK variant.

According to the research of Dr. Anurag Agarwal, Director of CSIR's laboratory Institute of Genomics and Integrative Biology (ICIB) and other scientists, the delta variant B.1.617 started growing in February-March. But at the end of March, changes were noted again in this variant. In one of its variants, a mutation E484Q was suddenly lost and a new mutation T478K was generated in its place. Thereafter, the rapid spread of the disease was observed.

 They have derived this result on the basis of genome sequencing of infected people done in Delhi, but a similar situation is expected to arise in almost the whole country. This new mutation i.e. B.1.617.2 has been cited as a cause of concern by Britain and WHO and it has spread to many countries of the world so far.

People infected again due to change

The study, published in the journal MedRxiv, claimed that after this mutation, the virus acquired the power to survive the immunity acquired by humans. As a result, people who had previously had corona infection, or who were found to be sero-positive in the past, also got re-infection. The IGIB is monitoring antibodies in some people. He found that during January-February, antibodies were reduced in sero-positive people. But in March it increased again. This means that they have got the infection for the second time.

Viral load is very high when infected with this variant

Research has said that in the Siro survey conducted in Delhi in December, antibodies were found in 56 percent of the people. But if the virus did not have the ability to escape resistance after the mutation, then people in Delhi would not have been infected on such a large scale. This is not the case in other provinces of the country where a significant population had been infected in the last wave. Cases of infection in people even after being vaccinated show that the new variant has the ability to avoid it. The research states that due to mutation upon mutation, the viral load was found to be very high in people infected with this variant. Which caused the disease to become more serious. Research has said that it is not yet confirmed that infection of the delta variant is also directly responsible for more deaths. However, research on this is still going on.